AML with t(16;16) or inv(16):
Typical immunophenotype for acute myeloid leukemia with t(16;16)(p13.1;q22) or inv(16)(p13.1q22); CBFB-MYH11 (see figures):
- Often myelomonocytic
- Myeloid blasts often CD34+, CD117+, CD13+ (most cases with homogenous bright expression), CD33+ (heterogenous), HLA-DR+
Presence of eosinophils with purple-violet granules larger than normal ones are typical morphologic findings.
Case 1:
Case 2:
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