Screening Flow Cytometry:

Each specimen that is received by the flow cytometry laboratory is accompanied by a requisition which indicates why the test is being performed.

The most common indications for flow cytometry are:

  • Suspicion of a lymphoproliferative neoplasm
  • Suspicion of acute leukemia

The indication is usually based on the clinical symptoms and the morphologic findings seen on a slide from that specimen.

In situations in which the morphology is ambiguous or cannot be assessed prior to flow cytometry analysis, a screening tube is helpful to try and capture the possible abnormal cell populations that might be present.

The types of specimens that could be analyzed include:

  • Peripheral Blood
  • Bone Marrow
  • Cerebrospinal Fluid (CSF)
  • Other fluids (pleural, ascites, bronchoalveolar lavage etc)
  • Lymph node (disaggregated)
  • Other tissues (disaggregated tumors)

Next page: Which antibodies are included in a screening tube?

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